Les membres du CSPBAT

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Céline Falentin-Daudré
Maître de Conférences - HDR
Equipe LBPS - CSPBAT- UMR 7244
Institut Galilée - Bâtiment E- Université Paris 13 (Bureau 419)
99 avenue JB Clément
93430 Villetaneuse (France)
Tel: 01 49 40 33 61
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Biographie

Le Dr C. Falentin-Daudré a effectué ses études supérieures à l’université de Picardie Jules Verne d’Amiens. Elle a ensuite poursuivi une thèse à l‘université de Picardie Jules Verne d’Amiens sous la direction du Dr Imane Stasik et du Pr Daniel Beaupère.
En 2009, elle a obtenu son doctorat sur le développement de nouvelles molécules actives à partir d’oses pour des applications dans le domaine médical. Après un stage post-doctoral en Belgique au CERM à l’université de Liège, elle a été nommée Maître de Conférences en septembre 2012 à l’université de Paris 13 dans le laboratoire LBPS-CSPBAT dirigé par le Pr V. Migonney. Elle a obtenu son HDR le 19 novembre 2019 au sein de l’Université Paris 13. Ses domaines d’expertises sont

1) le greffage de polymères bioactifs sur des surfaces métalliques et/ou polymères pour des applications biomédicales,

2) l’élaboration d’implant en polymère biodégradable par électrofilage pour des applications biomédicales. Depuis le 1er septembre 2016, elle est responsable de la mention M2 du Master SGM parcours I2B de l’Institut Galilée (Université Paris 13). Depuis le 29 novembre 2019, elle est membre de la section CNU 33 (Chimie des Matériaux).

Thème(s) de recherche

Publications

  1.  “Polymères bioactifs et implants biodégradables” Migonney V., Falentin-Daudré C., Actualité Chimique, Edition spéciale 50 ans GFP (Rubrique : Polymères, le futur. Polymères en émergence sur les enjeux sociétaux), Numéro 456, P 186, Novembre-décembre 2020.
  2. “Review of silicone surface modification techniques and coatings for antibacterial/antimicrobial applications: inspiring work to improve breast implants’ surfaces” Lam M., Migonney V., Falentin-Daudre C.*, Acta Biomaterialia, 2020, doi.org/10.1016/j.actbio.2020.11.020. (IF: 7,242) *Corresponding author
  3. “Chondrogenic differentiation of human bone marrow aspirates enhanced by overexpression of RAAV-SOX9 and TGF-ß upon vector delivery via pNaSS-grafted microstructured polycaprolactone scaffolds” Gross K., Venkatesan J. K., Falentin-Daudré C., Vaquette C., Migonney V., Cucchiarini M.*Osteoarthritis and Cartilage, 2020, 28, S520-S521. (IF: 4,793)
  4. “A simple way to graft bioactive polymer on silicone surfaces to improve the biological response” Lam M., Morris V., Humblot V., Migonney V., Falentin-Daudré C.*, European Polymer Journal, 2020, 128, 109608. (IF: 3,621) *Corresponding author
  5.  “Core-shell flower Nanoparticles: From chemical design to one step synthesis of hybrid gold nanoparticles and their interaction with human proteins” Falentin-Daudré C., Aitouakli M., Baumann J.S., Bouchemal N., Humblot V., Migonney V., Spadavecchia J., ACS Omega, 2020, 14, 8137-8145. (IF: 2,584)
  6.  “Enhanced chondrogenic differentiation activities in human bone marrow aspirates via sox9 overexpression mediated by pNaSS-grafted PCL film-guided rAAV gene transfer” Venkatesan J. K., Meng W., Rey-Rico A., Schmitt G., Speicher-Mentges S., Falentin-Daudré C., Leroux A., Madry H., Migonney V., Cucchiarini M.*, Pharmaceutics, 2020, 12 (3), 280. (IF: 4,773)
  7. “Microstructure and biological evaluation of nanocrystalline diamond films deposited on titanium substrates using distributed antenna array microwave system ” Dekkar D., Bénédic F., Falentin-Daudré C., Rangel A., Issaoui R., Achard J., Migonney V. Diamond and Related Materials, 2020, 103, 107700. (IF: 2,290)
  8.  “Nanostructured titanium alloy surface improving osteoblast response: a combination of topography and chemistry” Rangel, A. L. R., Falentin-Daudré C., Pimentel B., Vergani C., Migonney V., Alves Claro A. P. R. Surface and Coatings Technology, 2020, 383, 125226. (IF: 3,192)
  9. “Biomaterial-Guided rAAV Delivery from pNaSS-Grafted PCL Films to Target Human Bone Marrow Aspirates ” Venkatesan J. K., Falentin-Daudré C., Leroux A., Migonney V., Cucchiarini M. Tissue Engineering, 2019, doi: 10.1089/ten.TEA.2019.0165.
  10. “Electrospun Poly(ε-caprolactone) Fiber Scaffolds Functionalized by the Covalent Grafting of a Bioactive Polymer: Surface Characterization and Influence on in Vitro Biological Response” Amokrane G., Humblot V., Jubeli E., Yagoubi N., Ramtani S., Migonney V., Falentin-Daudré C.*, ACS Omega, 2019, 4 (17), 17194-17208.
  11. “Overexpressionof rAAV-SOX9 and TGF-B in human bone marrow aspirates upon vector delivery via pNaSS-coated poly(e-caprolactone) scaffolds” Venkatesan J. K., Falentin-Daudré C., Leroux A., Baumann J.-S., Migonney V., Cucchiarini M. Osteoarthritis and Cartilage, 2019, 27, S149-S150.
  12. “Investigation of a distributed antenna array microwave system for the three-dimensional low-temperature growth of nanocrystalline diamond films” Dekkar D., Benedic F., Falentin-Daudré C., Brinza O., Riadh I., Achard J. Diamond and Related Material, 2019, 84, 28-36.
  13. “Review of titanium surface modification techniques for antibacterial applications: physical modification, coating, grafting from and grafting to” Chouirfa H., Bouloussa H., Migonney V., Falentin-Daudré C.* Acta Biomaterialia, 2019, 83, 37-54.
  14. “Genetic modification of human bone marrow aspirates via delivery of rAAV vectors coated on on pNaSS-grafted poly(ε-caprolactone) scaffolds” Venkatesan J. K., Leroux A., Baumann J.-S., Rey-Rico A., Falentin-Daudré C., Frisch J., Madry H., Migonney V., Cucchiarini M. Osteoarthritis and Cartilage, 2018, 26 (1), S134-S135.
  15. “Controlled Release of Gene Therapy Constructs from Solid Scaffolds for Therapeutic Applications in Orthopedics” Venkatesan J., Falentin-Daudré C., Leroux A., Migonney V., Cucchiarini M. Discovery Medicine, 2018, 25 (138), 195-203.
  16. “A simple way to functionalize PCL surface by grafting bioactive polymers using UV irradiation” Amokrane G., Falentin-Daudré C.*, Ramtani S., Migonney V. IRBM, 2018, 39 (4), 268-278. (IF: 1,022) (IF JCR 2018: 0,934) *Corresponding author
  17. “Grafting of bioactive polymers with various architectures: a versatile tool for preparing antibacterial infection and biocompatible surface” Chouirfa H., Evans D. M., Bean P., Saleh-Mghir A., Crémieux A.-C., Castner D. G. C., Falentin-Daudré C., Migonney V. ACS Applied Materials & Interfaces, 2018, 10 (2), 1480-1491
  18. “Functionalization of new biocompatible titanium alloys with harmonic structure design by using UV irradiation” Amokrane G., Hocini A., Ameyama K., Dirras G., Migonney V., Falentin-Daudre C.* IRBM, 2017, 38, 190-197. (IF: 1,022) (IF JCR 2017: 0,897) *Corresponding author
  19. “Titanium alloy surface coating using poly(sodium styrene sulfonate) and poly(acrylic acid)” Zhang C. X., Falentin-Daudré C., Migonney V. Bio-Medical Materials and Engineering, 2017, 27 (6), 657-668. (IF: 1,243) (IF JCR 2017: 0,872)
  20. “Grafting of architecture controlled poly(styrene sodium sulfonate) onto titanium surfaces using bio-adhesive molecules: Surface characterization and biological properties” Chouirfa H., Evans D. M., Castner G., Bean P., Mercier D., Galtayries A., Falentin-Daudré C., Migonney V. Biointerphases, 2017, 12, 02C418.
  21. "Highly crystalline sphere and rod-shaped TiO2 nanoparticles: A facile route to Bio-polymer grafting" Falentin-Daudré C., Baumann J. S., Migonney V., Spadavecchia J. Frontiers in Laboratory Medicine, 2017, 1, 217-223.
  22. “Grafting of bioactive polymers onto titanium implants by UV irradiation” Chouirfa H., Migonney V., Falentin-Daudré C.* RCS Advances, 2016, 6, 13766-13771.
  23. “Mussel-inspired protein-repelling ambivalent block copolymers: controlled synthesis and characterization” Patil N., Falentin-Daudré C., Jérôme C., Detrembleur C. Polym. Chem., 2015, 6, 2919-2933.
  24. “Influence of alkyl chain length on the mesomorphism of 5-S-alkyl-5-thiopentonolactones and 5-S-alkyl-5-thiopentitols” Stasik I., Gottis S., Falentin-Daudré C., Meyer C. Carbohydrate Research, 2015, 392, 31-39.
  25. “Role of protein environment and bioactive polymer grafting in the S. epidermidis response to titanium alloy for biomedical applications” Vasconcelos D. M., Falentin-Daudré C., Blanquaert D., Thomas D., Granja P. L., Migonney V. Materials Science and Engineering: C, 2014, 45,176-18.
  26. “Catechols as versatile platforms in polymer chemistry” Faure E., Falentin-Daudré C., Jérôme C., Lykawa J., Fournier D., Woisel P., Detrembleur C. Progress in Polymer Science, 2013, 38, 236-270.
  27. “A poly(methacrylamide) bearing catechols as a macromolecular platform for imparting antibacterial, antibiofilm and antiadhesion activities to stainless steel” Faure E.‡, Falentin-Daudré C.‡, Farina F., Van De Weerdt C., Martial J., Jérôme C., Duwez A.-S., Detrembleur C. (‡: Co-auteurs 1:1) Advanced Functional Materials, 2012, 22, 5271-5282.
  28. “A green and bio-inspired process to afford durable antibiofilm property to stainless steel” Faure E., Vreuls C., Falentin-Daudré C., Zocchi G., Van De Weerdt C., Martial J., Jérôme C., Detrembleur C. Biofouling, 2012, 28, 719-728.
  29. “Antibacterial polyelectrolyte micelles for coating stainless steel” Falentin-Daudré C., Faure E., Svaldo-Lanero T., Jérôme C., Van De Weerdt C., Martial J., Duwez A.-S., Detrembleur C. Langmuir, 2012, 28, 7233-7241.
  30. “Synthesis of new N-subtituted 3,4,5-trihydroxypiperidin-2-ones from D-ribono-1,4-lactone” Falentin-Daudré C., Beaupère D., Stasik I., Carbohydr. Res. 2010, 345, 1983-1987.
  31. “Efficient synthesis of new N-alkyl-D-ribono-1,5-lactams from D-ribono-1,4-lactone” Falentin C., Beaupère D., Demailly G., Stasik I. Tetrahedron Lett., 2009, 50, 5364-5366.)
  32. “New approach to (-)-polyoxamic acid and 3,4-diepipolyoxamique acid from D-lyxono-1,4-lactone” Falentin C., Beaupère D., Demailly G., Stasik I. Tetrahedron, 2008, 64, 9989-9991.
  33. “A concise synthesis of 5-amino-5-deoxyaldonic acids as monomers for the preparation of Nylons 5” Falentin C., Beaupère D., Demailly G., Stasik I. Carbohydr. Res., 2007, 342, 2807-2809. “Rapid synthesis of oligosaccharides mimetics using click chemistry” Gouin S. G., Bultel L., Falentin C., Kovensky J. Eur. J. Org. Chem., 2007, 7, 1160-1167.

Chapitre d'ouvrage

“Functionalization of biomaterials and applications” Chapter, Biomaterials, Ed. Wiley, Falentin-Daudré C. ; Migonney V., 2014

Brevet

  1. Falentin-Daudré C. ; Migonney V. ; Chouirfa H. ; Baumann JS. “Procédé de greffage de polymères bioactifs sur des matériaux métalliques”, PCT/EP2016/068909.
  2. Valentin-Daudré C. ; Migonney V. ; Chouirfa H. ; Baumann JS. “Process for grafting bioactive polymers onto metallic materials”, Extension brevet WO/2017/025519.

Enseignement

Techniques

Electrospinning, Spectromètre FTIR-ATR, Spectromètre UV, MEB-EDX, Angle de contact, Ozonateur, Spin-coater, lampe UV, AFM, RMN, DSC, SEC.

 

 

Informations utiles