Team LBPS - CSPBAT- UMR 7244

Institut Galilée, Batiment E 4ème étage (Bureau E 405)
99 Avenue JB Clément
93430 Villetaneuse (France)
Tel : +33 (0)1 49 40 33 52 (3346)

Email: Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser.



Véronique Migonney received an Engineer Diploma in Materials Sciences (1981), a Master in Biomedical and Biomaterials Engineering (1982) and a PhD (1986) in Chemistry (Doctorat d’Etat Es Sciences Physiques spécialité Chimie – supervisor M. Jozefowicz) from University Paris 13th. Véronique Migonney was director of the laboratory CSPBAT UMR 7244 CNRS UP13 from 2009 to 2016 and heads the team LBPS devoted to Biomaterials Sciences from 2002. She set up and headed the Master of Chemistry and Health Engineering from 2004 to 2016. Véronique Migonney is Fellow of the International College of Fellows in Biomaterials Science and Engineering for her contribution to the functionalization of biomaterials surfaces. She was president of the French Society for Biomedical Engineering 2011-2013 and she is vice-president of the AGBM (Alliance pour le Génie Biologique et Médical). Her expertise is focused on biomaterials science: she is working for > 35 years in the field of bioactive polymers synthesis and grafting to functionalize biomaterials surfaces with the aim of controlling the host response.


Themes of research

Chemistry of Biomaterials
Functionalization of polymeric and metallic surfaces by polymer grafting techniques
Bioactive surfaces and control of the host response
Bioactive implants and prostheses for orthopedic applications

Significant Publications ( 2013 - today)

Chouirfa H., H Bouloussa, Migonney V., Falentin-Daudré C. Review of titanium surface modification techniques and coatings for antibacterial applications. Acta Biomaterialia 2018 in press

Leroux A., Maurice E., Viateau V., Migonney V.;Feasibility study of the elaboration of a biodegradable and bioactive ligament made of poly(ε-caprolactone)-pNaSS grafted fibers for the reconstruction of anterior cruciate ligament: in vivo experiment. IRBM 2018 in press

Leroux A., Egles C., Migonney V.;Impact of chemical and physical treatments on the mechanical properties of poly(ε-caprolactone) fibers bundles for the anterior cruciate ligament reconstruction Plos One 2018 13 (10), e0205722

JK Venkatesan, C Falentin-Daudré, A Leroux, V Migonney, M Cucchiarini Controlled release of gene therapy constructs from solid scaffolds for therapeutic applications in orthopedics.Discovery medicine 25 (138), 195-203

Hamza Chouirfa, Margaret D. M. Evans, Penny Bean, Azzam Saleh-Mghir, Anne Claude Crémieux,David G. Castner, Céline Falentin-Daudré, Véronique Migonney Grafting of bioactive polymers with various architectures: a versatile tool for preparing antibacterial infection and biocompatible surface. ACS Appl Mater Interfaces. 2018; 10:1480-1491

C Falentin-Daudré, JS Baumann, V Migonney, J Spadavecchia, Highly crystalline sphere and rod-shaped TiO 2 nanoparticles: A facile route to bio-polymer grafting Frontiers in Laboratory Medicine. 2017 1 (4), 217-223
Chouirfa H, Evans MDM, Castner DG, Bean P, Mercier D, Galtayries A, Falentin-Daudré C, Migonney V. Grafting of architecture controlled poly(styrene sodium sulfonate) onto titanium surfaces using bio-adhesive molecules: Surface characterization and biological properties Biointerphases. 2017 Jun 14;12(2):02C418. doi: 10.1116/1.4985608.

G Amokrane, A Hocini, K Ameyama, G Dirras, V Migonney, Functionalization of NewBiocompatible Titanium Alloys with Harmonic Structure Design by Using UV IrradiatioN, IRBM 2017. 38 (4), 190-197,

1. HP Felgueiras, A Decambron, M Manassero, L Tulasne, MDM Evans, V Migonney, Bone tissue response induced by bioactive polymer functionalized Ti6Al4V surfaces: In vitro and in vivo study, Journal of Colloid and Interface Science 2017; 491: 44-54,
2. Felgueiras HP, Sanjeeva NS, Sommerfeld SD, Brás M, Migonney V, Kohn J. Competitive adsorption of plasma proteins using quartz crystal microbalance. Appl Mater Interfaces. 2016; 8:13207-13217.
3. H Chouirfa, V Migonney, C Falentin-Daudré Grafting bioactive polymers onto titanium implants by UV irradiation, , RSC Advances 2016 6 (17), 13766-13771
4. Felgueiras HP, Ben Aissa I, Evans MD, Migonney V. Contributions of adhesive proteins to the cell and bacteria response to surfaces treated with bioactive polymers: case of poly(sodium styrene sulfonate) grafted titanium surfaces. J Mater Sci Mater Med. 2015; 26:261-275.
5. Rohman, G., Huot, S., Vilas-Boas, M., Radu-Bostan, G., Castner, DG, Migonney, V The grafting of a thin layer of poly(sodium styrene sulfonate) onto poly(ε-caprolactone) surface can enhance fibroblast behavior,. J Mater Sci Mater Med. 26(7):206. 2015.

6. Felgueiras, H., Ben Aissa, I., Evans, M., Migonney, V., Contributions of adhesive proteins to the cell and bacteria response to surfaces treated with bioactive polymers: case of poly(sodium styrene sulfonate) grafted titanium surfaces, J Mater Sci Mater Med., 26(11):261, 2015

7. Felgueiras, H., Evans, M., Migonney, V.,Contribution of fibronectin and vitronectin to the adhesion and morphology of MC3T3-E1 osteoblastic cells to poly(NaSS) grafted Ti6Al4V Acta. Biomat, 28:225-33, 2015

8. S. Guérard, M. Manassero, V. Viateau, V. Migonney, W. Skalli, D. Mitton,Biomechanical evaluation of a bioactive artificial anterior cruciate ligament, Advances in Biomechanics & Applications, An International Journal" 2015, 1 (4) ; 239-252

9. D.M. Vasconcelos, C. Falentin-Daudré, D. Blanquaert, D. Thomas, P. L. Granja, V. Migonney. Role of protein environment and bioactive polymer grafting in the S. epidermidis response to titanium alloy for biomedical applications, Materials Science and Engineering: C, 2014 Dec ;45 :176-183
10. Felgueiras HP, Sommerfeld SD, Murthy NS, Kohn J, Migonney V Poly(NaSS) Functionalization Modulates the Conformation of Fibronectin and Collagen Type I To Enhance Osteoblastic Cell Attachment onto Ti6Al4V,. Langmuir. 2014 Aug 12;30(31):9477-83
11. G. Zorn, V. Migonney, D. Castner. Grafting titanium nitride surfaces with sodium styrene sulfonate thin films", Biointerphases 2014 ; 9 (3)
12. Felgueiras H, Migonney V. Sulfonate groups grafted on Ti6Al4V favor MC3T3-E1 cell performance in serum free medium conditions, Materials Science and Engineering: C 2014. ; 39, 196-202
13. Djaker N, Brustlein S, Rohman G, Huot S, de la Chapelle ML, Migonney V, Characterization of a synthetic bioactive polymer by nonlinear optical microscopy, Biomed Opt Express. 2014; 5(1):149-57.
14. C. Vaquette, V. Viateau, S. Guérard, F. Anagnostou, M. Manassero, D.G. Castner, V. Migonney, The effect of polystyrene sodium sulfonate grafting on polyethylene terephthalate artificial ligaments on in vitro mineralization and in vivo bone tissue integration Biomaterials 2013 34(29) 7048-6
15. Huot S, Rohman G, Riffault M, Pinzano A, Grossin L, Migonney V Increasing the bioactivity of elastomeric poly(ε-caprolactone) scaffolds for use in tissue engineering,. Biomed Mater Eng. 2013;23(4):281-8.
16. Viateau V, Manassero M, Anagnostou F, Guérard S, Mitton D, Migonney V. Biological and biomechanical evaluation of the ligament advanced reinforcement system (LARS AC) in a sheep model of anterior cruciate ligament replacement: a 3-month and 12-month study, Arthroscopy. 2013 Jun;29(6):1079-88
17. Alcheikh A, Pavon-Djavid G, Helary G, Petite H, Migonney V, Anagnostou F. PolyNaSS grafting on titanium surfaces enhances osteoblast differentiation and inhibits Staphylococcus aureus adhésion, J Mater Sci Mater Med. 2013 Jul;24(7):1745-54.

Books and book chapters

Edition de l’ouvrage “Biomaterials”, V. Migonney, ISTE - Wyley, 2014 November, ISBN: 978-1-84821-585-6, 248 pages
Migonney V. Chap 1 « History of Biomaterials », Véronique Migonney in Biomaterials, ISTE - Wyley, (2014) ISBN: 978-1-84821-585-6, pp 1-10 (2014)
Migonney V Chap 2 « Definitions », Véronique Migonney in Biomaterials, ISTE - Wyley(2014) ISBN: 978-1-84821-585-6, pp 11-24
Migonney V « Biocompatibility and Norms », Véronique Migonney in Biomaterials, ISTE – Wyley, (2014) ISBN: 978-1-84821-585-6, pp 83-98
Migonney V « Bioactive Polymers and Surfaces: A Solution for Implant Devices », Véronique Migonney in Biomaterials, ISTE - Wyley, (2014) ISBN: 978-1-84821-585-6, pp 101-113

Scientific Production
Patents: 23
Publications: >100 articles, 14 proceedings, >150 communications, 65 invited communications, 10 book chapters

Macromolecular chemistry, Biomaterials Science, Biocompatibility, Host response

Industrial Partnership
LARS, Ceraver, Iceram, texinov

Scientific programme
BPI granted LIGA2BIO: UP13, Lars, Texinov + UTC, ENSAM, UPMC, ENVA